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Predisposition

/prˌidɪspəˈzɪʃən/
C1
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(noun) The state of being predisposed or susceptible to something, especially to a behavior or a health condition.

Hallucinogen use can trigger certain psychiatric conditions in people with a predisposition to them.
CEFR Practice Quiz
His ____ toward anxiety made stressful situations particularly difficult for him to manage.

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