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Loneliness

/lˈoʊnlinəs/
B1
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(noun) A feeling of depression resulting from being alone or from having no companions.

The worst loneliness is to not be comfortable with yourself.
His loneliness was as deep as the blue of the ocean around his dugout canoe.
CEFR Practice Quiz
Many elderly people suffer from a deep sense of ____ after their children move away to start lives today.

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