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Isolation

/ˌaɪsəˈleɪʃən/
C1
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(noun) The state of being isolated, detached, or separated; the state of being away from other people.

We shouldn't confuse solitude with isolation. They are two separate things.
Isolation is the common lot of man.
CEFR Practice Quiz
Spending many days in total ____ can have a negative effect on a person's mental health and well-being.

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