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Antagonist

/æˈntæɡənəst/
C2
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(noun) An opponent or enemy.

Caffeine is a purinergic antagonist that competitively inhibits adenosine at the sites of P1 receptors.
The antagonist of the book was introduced on the second page.
CEFR Practice Quiz
The main ____ in the story was a powerful and evil wizard from afar.

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