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Aggravation

/ˌæɡrəˈveɪʃən/
C2
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(noun) The act of aggravating, or making worse; used of evils, natural or moral; the act of increasing in severity or heinousness; something additional to a crime or wrong and enhancing its guilt or injurious consequences.

I have aggravation after eating.
That would've saved a lot of aggravation.
CEFR Practice Quiz
The constant noise from the street was a major ____ to the residents.

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